Acute inflammatory Response to Manual Lymph Drainage Massage in Breast Cancer Related Lymphedema

Mohamed, Mahmoud; Abd El-Hakim, Ahmed Abd EL-monem; Mahmoud, Mahmoud Abdel-Tawab

doi:10.21608/ejpt.2022.128117.1075

Acute inflammatory Response to Manual Lymph Drainage Massage in Breast Cancer Related Lymphedema

Document Type : Original Article

Authors

¹ Department of Physical therapy for surgery,Faculty of Physical Therapy Ahram Canadian University, Giza,Egypt

² Department of Physical Therapy for Basic Sciences, Faculty of Physical Therapy, Beni-Suef University, Egypt

³ Department of Surgery, Faculty of Medicine, Fayoum University, Egypt

10.21608/ejpt.2022.128117.1075

Abstract

Abstract:
Purpose: To evaluate the effect of manual lymphatic drainage (MLD) on the acute inflammatory response and arm circumference in women suffering from breast cancer-related lymphedema (BCRL).Methods: Single-arm study (Pretest – Posttest) design. 35 women with unilateral BCRL were received 1 session of 45 minute of MLD. Inflammatory Markers (IL-6, and CRP), and arm circumference were evaluated before and 24 hours after application of MLD.
Results: The statistical analysis by The Wilcoxon signed ranks test found that there was a significant (P = 0.02; P < 0.05) decrease in arm circumference post treatment compared to pre treatment. But, no remarkable differences (P = 0.648 & 0.874; P > 0.05) between post treatment and pre treatment of IL6 & CRP within study group.
Conclusion: According to prior discussions of these findings and a review of academic research related to the current study, MLD is a straightforward, safe, and effective method for the treatment of BCRL that did not result in a substantial rise in IL6 or CRP as inflammatory mediators.

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